Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 5, 2019Catheterization and Cardiovascular Interventions

An under‐recognized high‐risk atrial fibrillation population: Analyzing transcatheter mitral valve repair patients for left atrial appendage closure device application

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Patients undergoing TMVR have a high incidence of AF, and their comorbidities increase both stroke and bleeding risks, making stroke prophylaxis problematic.

Population

Patients undergoing TMVR for degenerative mitral valve disease

Comparison

Evaluation of candidacy for a LAAC device

Design

Single-center retrospective study

Authors

CLColleen E. LaneMEMackram F. EleidDHDavid R. Holmes

Discussion

Loading...

Member takes

Overview

May identify TMVR patients for adjunctive LAAC; hypothesis-generating and leaves optimal strategy open.

Structured PICO

P
Population
Patients undergoing transcatheter mitral valve repair (TMVR) for degenerative mitral valve disease. 122 (62%) had atrial fibrillation.
I
Intervention
Assessment for left atrial appendage closure (LAAC) device candidacy
O
Outcome
Candidacy for a LAAC device for stroke prevention as an alternative to chronic anticoagulation based on bleeding and stroke risk assessments

A significant proportion (50%) of patients undergoing TMVR are candidates for LAAC due to high rates of concurrent atrial fibrillation and elevated bleeding and stroke risks.

Cite This Study

Lane et al. (2019) studied this question.

synapsesocial.com/papers/6a952d6d420bcbf9d0168ef1https://doi.org/10.1002/ccd.28220
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left Atrial Appendage Closure as an Alternative to Warfarin for Stroke Prevention in Atrial Fibrillation2015 · 548 citations
  2. 25-Year Outcomes After Left Atrial Appendage Closure2017 · 1,031 citations
  3. 3Effects of Non–Vitamin K Antagonist Oral Anticoagulants Versus Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: A Systematic Review and Meta‐Analysis2017 · 152 citations
  4. 4The HAS-BLED Score Identifies Patients with Acute Venous Thromboembolism at High Risk of Major Bleeding Complications during the First Six Months of Anticoagulant Treatment2015 · 95 citations
  5. 5The CHA2DS2-VASc score identifies those patients with atrial fibrillation and a CHADS2 score of 1 who are unlikely to benefit from oral anticoagulant therapy2012 · 190 citations