Why the study?
The prognostic implications of combined pre- and post-capillary pulmonary hypertension in patients with PH-LHD remained controversial.
Does combined pre- and post-capillary pulmonary hypertension (Cpc-PH) worsen cardiac outcomes in patients with symptomatic heart failure compared to other pulmonary hypertension profiles?
Does combined pre- and post-capillary pulmonary hypertension (Cpc-PH) worsen cardiac outcomes in patients with symptomatic heart failure compared to other pulmonary hypertension profiles?
In patients with symptomatic heart failure, the presence of combined pre- and post-capillary pulmonary hypertension (Cpc-PH) is associated with significantly worse long-term cardiac outcomes compared to isolated post-capillary PH or no PH.
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Cpc-PH flags higher-risk HF patients under new criteria; supports refined stratification yet leaves practice change to prospective trials.
Ibe et al. (2021) studied this question.
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