Why the study?
Does argatroban improve neurological symptoms and daily living activities in patients with acute cerebral thrombosis?
Population
Patients with acute cerebral thrombosis
Comparison
Argatroban administered by slow intravenous… vs Placebo with concomitant glycerol as basic therapy
Design
RCT, double-blind
Authors
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Supports argatroban in acute cerebral thrombosis; extends RCT evidence for direct thrombin inhibition in ischemic stroke.
Does argatroban improve neurological symptoms and daily living activities in patients with acute cerebral thrombosis?
Argatroban is an effective and safe treatment for improving neurological symptoms and daily living activities in acute cerebral thrombosis, particularly when administered early.
Kobayashi et al. (1997) studied this question.
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