What question did this study set out to answer?

To report a rare case of hypereosinophilic syndrome presenting with bilateral ventricular thrombi and the FIP1L1/PDGFRA genetic fusion.

June 9, 2010Echocardiography

Hypereosinophilic Syndrome Presenting with Biventricular Cardiac Thrombi

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Population

50-year-old male with hypereosinophilic syndrome with FIP1L1/PDGFRA fusion presenting with biventricular…

Design

Case_report

Authors

ALAnkur LodhaLouisiana State University MHMehandi HaranMaimonides Medical Center VSVijay ShettyMaimonides Medical Center

Discussion

Member takes

Implication

May alert clinicians to biventricular thrombi in FIP1L1/PDGFRA-positive hypereosinophilic syndrome; hypothesis-generating for prevalence studies.

Key Points

To report a rare case of hypereosinophilic syndrome presenting with bilateral ventricular thrombi and the FIP1L1/PDGFRA genetic fusion.
Clinical evaluation and diagnostic workup of a 50-year-old male with hypereosinophilia and cardiac involvement.
Cardiovascular assessment and genetic testing to evaluate cardiac structural complications and detect oncogenic fusion transcripts.
Detected simultaneous thrombus formation in both the left and right cardiac ventricles secondary to eosinophilic infiltration.
Confirmed the presence of the FIP1L1/PDGFRA gene fusion, a molecular marker linked to eosinophilia-associated endomyocardial disease.

Structured PICO

Population

50-year-old male with hypereosinophilic syndrome with FIP1L1/PDGFRA fusion presenting with biventricular cardiac thrombi

This case highlights a rare presentation of hypereosinophilic syndrome complicated by biventricular cardiac thrombi.

Cite This Study

Lodha et al. (2010) studied this question.

synapsesocial.com/papers/6a953ba71fe04514d10f4cd5 https://doi.org/10.1111/j.1540-8175.2009.01144.x

Topics

Echocardiography

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Implication

May alert clinicians to biventricular thrombi in FIP1L1/PDGFRA-positive hypereosinophilic syndrome; hypothesis-generating for prevalence studies.

Hypereosinophilic Syndrome Presenting with Biventricular Cardiac Thrombi

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Hypereosinophilic Syndrome Presenting with Biventricular Cardiac Thrombi

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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