Why the study?
Does thyroidectomy or thyroid hormone administration alter bile cholesterol and cholic acid concentrations?
Population
Animal model (not explicitly specified in abstract)
Comparison
Thyroidectomy, administration of… vs Control/baseline (implied)
Design
Preclinical
Authors
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Rat data do not guide thyroid or biliary care; leaves open human translation of thyroid-bile effects.
Does thyroidectomy or thyroid hormone administration alter bile cholesterol and cholic acid concentrations?
Thyroidectomy and low iodine diet reduce bile cholesterol and cholic acid, while prolonged T3 or TA3 administration reduces biliary cholic acid without increasing bile cholesterol.
A. Van Zyl (1957) studied this question.
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