Key result
Phenoxybenzamine hydrochloride prevented acute urinary retention after inguinal hernioplasty, with 0% incidence in the treated group compared to 59.1% in the control group.
Why the study?
Does phenoxybenzamine hydrochloride prevent acute urinary retention in patients over 60 years undergoing inguinal hernioplasty?
RCT (n=102)
randomized
Does phenoxybenzamine hydrochloride prevent acute urinary retention in patients over 60 years undergoing inguinal hernioplasty?
Phenoxybenzamine hydrochloride effectively prevents acute urinary retention in older patients undergoing inguinal hernioplasty.
In a prospective, randomized study, 102 patients over the age of 60 years underwent inguinal hernioplasty. We compared a group of 58 patients who received phenoxybenzamine hydrochloride with a control group of 44 patients. The phenolsulfonphthalein test was performed in all patients. Twenty-six (25.5%) of the 102 patients developed acute urinary retention after the hernioplasty; all of them were in the control group. All of these 26 patients had pathological phenolsulfonphthalein test. In 21 of these 26 patients, urinary retention disappeared within 48 hours following phenoxybenzamine administration.
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Gideon Goldman (1988) conducted an RCT in inguinal hernioplasty (n=102). phenoxybenzamine hydrochloride vs. control group was evaluated on acute urinary retention after hernioplasty. Phenoxybenzamine hydrochloride prevented acute urinary retention after inguinal hernioplasty, with 0% incidence in the treated group compared to 59.1% in the control group.
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