Key result
Platelet pathology occurs in early idiopathic scoliosis but cannot be used as a prognostic indicator of curve progression over a 2- to 3.5-year follow-up.
Why the study?
Can platelet pathology predict curve progression in adolescents with minimal curve idiopathic scoliosis?
Population
Adolescents with minimal curve idiopathic scoliosis (7-18 degrees) and healthy control subjects
Comparison
Platelet tests vs Healthy control subjects
Design
Cohort
Follow-up
2- to 3.5-year
Authors
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Platelet testing should not guide progression risk in early scoliosis; leaves open whether other biomarkers predict curve progression.
Cohort
Can platelet pathology predict curve progression in adolescents with minimal curve idiopathic scoliosis?
Platelet pathology occurs in early idiopathic scoliosis but cannot be used as a prognostic indicator of curve progression.
Meyer et al. (1987) conducted a cohort in Minimal curve idiopathic scoliosis. Platelet pathology (morphometry, calcium content, surface negative charge) vs. Healthy control subjects was evaluated on Prediction of curve progression. Platelet pathology occurs in early idiopathic scoliosis but cannot be used as a prognostic indicator of curve progression over a 2- to 3.5-year follow-up.
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