Why the study?
Does the enkephalinase inhibitor phosphoramidon potentiate substance P- and capsaicin-induced bronchial smooth muscle contractions in human tissues?
Population
Human bronchial tissues from at least 14 patients
Comparison
Substance P and capsaicin in the presence of… vs Substance P and capsaicin alone, or in the…
Design
Preclinical
Authors
Loading...
Enkephalinase inhibition enhances tachykinin effects in animal airways; leaves open translation to human bronchus.
Does the enkephalinase inhibitor phosphoramidon potentiate substance P- and capsaicin-induced bronchial smooth muscle contractions in human tissues?
Enkephalinase regulates the contractile effects of exogenous substance P and endogenous tachykinins in the human bronchus.
Honda et al. (1991) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: