Key result
Having multiple cytokines in the highest tertile increased the likelihood of having metabolic syndrome in both obese (P for trend=0.002) and non-obese older adults (P for trend=0.001).
Why the study?
Are adipocytokines associated with metabolic syndrome in older adults with and without obesity?
Population
944 community-dwelling adults aged 65 years and older living in Tuscany, Italy.
Design
Cross-sectional
Authors
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Intense pro-inflammatory states may flag higher metabolic syndrome risk in older adults; hypothesis-generating and leaves open causal and clinical implications.
Cross-Sectional (n=944)
Are adipocytokines associated with metabolic syndrome in older adults with and without obesity?
p-value: p=0.002 (obese), 0.001 (non-obese)
An intense pro-inflammatory state, characterized by high levels of multiple cytokines, is associated with an increased likelihood of metabolic syndrome in both obese and non-obese older adults.
Stenholm et al. (2009) conducted a cross-sectional in Metabolic syndrome (n=944). High levels of multiple cytokines vs. Lower levels of cytokines was evaluated on Metabolic syndrome (MetS) (p=0.002 (obese), 0.001 (non-obese)). Having multiple cytokines in the highest tertile increased the likelihood of having metabolic syndrome in both obese (P for trend=0.002) and non-obese older adults (P for trend=0.001).
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