Key result
The extent of primary repair for type A aortic dissection had no significant influence on the 5-year freedom from distal (96.9%, P=0.22) or proximal (97.8%, P=0.84) reoperation.
Why the study?
Does the extent of primary aortic repair influence the incidence of reoperations after surgery for type A aortic dissection?
Cohort (n=1,159)
Yes
Does the extent of primary aortic repair influence the incidence of reoperations after surgery for type A aortic dissection?
p-value: p=0.22
The extent of primary repair for type A aortic dissection in low- to medium-volume centers does not significantly influence midterm reoperation rates or survival.
Supports limited primary repair for low reoperation risk in type A dissection; leaves open whether extensive approaches benefit high-risk subgroups.
OBJECTIVES: To describe the relationship between the extent of primary aortic repair and the incidence of reoperations after surgery for type A aortic dissection. METHODS: A retrospective cohort of 1159 patients treated for type A aortic dissection at eight Nordic low- to medium-sized cardiothoracic centers from 2005 to 2014. Data were gathered from patient records and national registries. Patients were separately divided into 3 groups according to the distal anastomoses technique (ascending aorta [n = 791], hemiarch [n = 247], and total arch [n = 66]), and into 2 groups for proximal repair (aortic root replacement [n = 285] and supracoronary repair [n = 832]). Freedom from reoperation was estimated with cumulative incidence survival and Fine-Gray competing risk regression model was used to identify independent risk factors for reoperation. RESULTS: The median follow-up was 2.7 years (range, 0-10 years). Altogether 51 out of 911 patients underwent reoperation. Freedom from distal reoperation at 5 years was 96.9%, with no significant difference between the groups (P = .22). Freedom from proximal reoperation at 5 years was 97.8%, with no difference between the groups (P = .84). Neither DeBakey classification nor the extent of proximal or distal repair predicted freedom from a later reoperation. The only independent risk factor associated with a later proximal reoperation was a history of connective tissue disease. CONCLUSIONS: Type A aortic dissection repair in low- to medium-volume centers was associated with a low reoperation rate and satisfactory midterm survival. The extent of the primary repair had no significant influence on reoperation rate or midterm survival.
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Pan et al. (2018) conducted a cohort in Type A aortic dissection (n=1,159). Extent of primary aortic repair vs. Different extents of repair (e.g., ascending aorta vs hemiarch vs total arch) was evaluated on Freedom from reoperation (p=0.22). The extent of primary repair for type A aortic dissection had no significant influence on the 5-year freedom from distal (96.9%, P=0.22) or proximal (97.8%, P=0.84) reoperation.
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