Key result
Young patients (≤45 years) with STEMI treated by primary PCI had significantly lower all-cause mortality than older patients (2.7% vs. 7.6%; adjusted HR 0.12, 95% CI 0.04-0.38).
Why the study?
Does young age (≤ 45 years) reduce all-cause mortality and major adverse cardiovascular events in patients with STEMI treated by primary PCI compared to older patients?
Population
3,618 patients with ST-elevation myocardial infarction treated by primary percutaneous coronary intervention…
Comparison
Young age (≤ 45 years) vs Older age (> 45 years)
Design
Cohort
Follow-up
median 3.0 (interquartile range 1.2-4.6) years
Authors
Loading...
Younger STEMI patients show lower mortality after primary PCI; extends age-outcome data but leaves open targeted strategies.
Cohort (n=3,618)
No
Does young age (≤ 45 years) reduce all-cause mortality and major adverse cardiovascular events in patients with STEMI treated by primary PCI compared to older patients?
Hazard Ratio: 0.12 (95% CI 0.04–0.38)
Absolute Event Rate: 2.7% vs 7.6%
p-value: p=<0.0001
Young patients (≤ 45 years) presenting with STEMI for primary PCI have an atypical risk factor profile (more often male, smokers, South Asian ethnicity) but excellent long-term outcomes compared to older patients.
Rathod et al. (2015) conducted a cohort in ST-elevation myocardial infarction (STEMI) (n=3,618). Young age (≤ 45 years) vs. Older age (> 45 years) was evaluated on all-cause mortality (HR 0.12, 95% CI 0.04-0.38, p=<0.0001). Young patients (≤45 years) with STEMI treated by primary PCI had significantly lower all-cause mortality than older patients (2.7% vs. 7.6%; adjusted HR 0.12, 95% CI 0.04-0.38).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: