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The following heptapeptides and octapeptides have been synthesized: (des‐Asp1)‐L‐Arg2(NO2)‐Ile5‐angiotensin II, (des‐Asp1)‐D‐Arg2(NO2)‐Ile5‐angiotensin II, D‐Asp(NH2)1‐Ile5‐angiotensin II, D‐Asp(NH2)5‐D‐Arg2‐Ile5‐angiotensin II, Gly1‐D‐Arg2‐Ile5‐angiotensin II, Asp1(NH2)‐Cit2‐Ile 5−‐angiotensin II*. Possible structure‐activity relationships are discussed.
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Schattenkerk et al. (1965) studied this question.
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