Why the study?
Does plasma renin activity predict cure by nephrectomy in hypertensive patients with seemingly unilateral renal parenchymal disease?
Population
62 hypertensive patients with seemingly unilateral renal parenchymal disease
Design
Cohort
Authors
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High plasma renin activity is uncommon and rarely predictive of cure in this cohort; leaves open whether renin assessment should guide nephrectomy decisions.
Does plasma renin activity predict cure by nephrectomy in hypertensive patients with seemingly unilateral renal parenchymal disease?
Abnormal renal-vein and peripheral renin values should be a prerequisite for advising nephrectomy in hypertensive patients with seemingly unilateral renal parenchymal disease, as most do not have renin-dependent hypertension.
E. Darracott Vaughan (1975) studied this question.
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