Why the study?
Does fish oil improve insulin sensitivity and plasma lipoproteins in NIDDM patients with hypertriglyceridemia?
Population
16 NIDDM patients with hypertriglyceridemia (triglyceride [TG], 2.25-5.65 mmol/l)
Comparison
Fish oil vs Placebo
Design
RCT, randomized with a parallel group sequence, double-blind, placebo-controlled
Follow-up
6 months
Authors
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Supports fish oil for TG lowering in hypertriglyceridemic NIDDM without insulin sensitivity concerns; extends evidence decoupling lipid from glycemic effects.
Does fish oil improve insulin sensitivity and plasma lipoproteins in NIDDM patients with hypertriglyceridemia?
Moderate fish oil supplementation in NIDDM patients with hypertriglyceridemia significantly reduces plasma triglycerides and NEFA without deteriorating blood glucose control, but does not improve insulin sensitivity.
Rivellese et al. (1996) studied this question.
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