Key result
Fever induced a type 1 Brugada syndrome electrocardiogram pattern in a 65-year-old black African man, which normalized upon resolution of the fever.
Case Report (n=1)
No
Fever can unmask a type 1 Brugada ECG pattern in patients without a history of syncope or family sudden death, highlighting the importance of ECG screening during infectious syndromes.
May prompt ECG review during fever even without syncope history; leaves open whether screening changes outcomes in asymptomatic patients.
Brugada syndrome is a channelopathy that can be familial or sporadic. It is a major cause of sudden death in young people with no obvious heart structural abnormality. The electrocardiogram can be dynamic over time with sometimes normalization. Several pathophysiological conditions are known to induce the electrocardiographic expression of the syndrome. We report here the case of a 65-year-old hypertensive man, without syncope or family sudden death history who was hospitalized for shigella gastroenteritis. Electrocardiogram during fever showed an incomplete block and ST segment elevation with negative T waves in V1 and V2 suggested type 1 Brugada syndrome. Troponin was negative. Electrocardiogram after fever recovered an incomplete right block and normalization of the ST segment. Electrocardiogram should be performed in patients admitted to the emergency unit for infectious syndrome in our countries. This may reveal a number of patients with Brugada syndrome abnormalities.
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Pessinaba et al. (2020) conducted a case report in Brugada Syndrome (n=1). Fever vs. Apyrexia was evaluated on Electrocardiogram pattern. Fever induced a type 1 Brugada syndrome electrocardiogram pattern in a 65-year-old black African man, which normalized upon resolution of the fever.
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