Key result
Short-term spinal cord stimulation therapy increased global myocardial perfusion reserve from 1.7 at baseline to 2.0 (P=0.02) in patients with refractory angina pectoris.
Why the study?
Does short-term spinal cord stimulation improve myocardial ischaemia tolerance and myocardial perfusion reserve in patients with refractory angina pectoris?
Population
18 patients with refractory angina pectoris
Comparison
Epidural spinal cord stimulation therapy for 3… vs Baseline (before starting therapy)
Design
Cohort
Follow-up
3 weeks
Authors
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Short-term SCS may improve perfusion reserve in refractory angina; hypothesis-generating and requires randomized confirmation before practice change.
Observational (n=18)
Does short-term spinal cord stimulation improve myocardial ischaemia tolerance and myocardial perfusion reserve in patients with refractory angina pectoris?
Absolute Event Rate: 2% vs 1.7%
p-value: p=0.02
Short-term spinal cord stimulation improves myocardial perfusion reserve and endothelium-mediated vasomotor function in patients with refractory angina pectoris, suggesting alleviation of perfusion abnormalities.
Saraste et al. (2014) conducted an observational in refractory angina pectoris (n=18). Epidural spinal cord stimulation (SCS) vs. Baseline (before starting therapy) was evaluated on Global myocardial perfusion reserve (MPR) (p=0.02). Short-term spinal cord stimulation therapy increased global myocardial perfusion reserve from 1.7 at baseline to 2.0 (P=0.02) in patients with refractory angina pectoris.
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