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September 1, 1993European Heart Journal

Assessment of the influence of spinal cord stimulation on left ventricular function in patients with severe angina pectoris: an echocardiographic study

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Why the study?

Does spinal cord stimulation prevent deterioration of left ventricular function during adenosine provocation in patients with severe intractable angina?

Population

15 patients with severe intractable angina pectoris despite optimal medical treatment and previous CABG…

Comparison

Spinal cord stimulation during adenosine… vs Control session without treatment during…

Design

Other

Authors

VKVuk KujacicSahlgrenska University HospitalTET. EliassonUniversity of GroningenCMClas MannheimerSahlgrenska University Hospital

Discussion

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Implication

SCS may attenuate adenosine-induced LV dysfunction in refractory angina; hypothesis-generating and requires randomized outcome trials.

Structured PICO

Does spinal cord stimulation prevent deterioration of left ventricular function during adenosine provocation in patients with severe intractable angina?

P
Population
15 patients with severe intractable angina pectoris despite optimal medical treatment and previous CABG, multi-vessel disease and graft occlusion or stenosis, mean age 64 years (range 49-71).
I
Intervention
Spinal cord stimulation (SCS) during adenosine provocation.
C
Comparator
Control session without treatment during adenosine provocation.
O
Outcome
Left ventricular ejection fraction assessed echocardiographically during adenosine provocation.surrogate

Spinal cord stimulation may attenuate ischemia-induced left ventricular dysfunction during adenosine provocation in patients with refractory angina.

Cite This Study

Kujacic et al. (1993) studied this question.

synapsesocial.com/papers/6a95b57e223f4b595a4f0972https://doi.org/10.1093/eurheartj/14.9.1238
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of spinal cord stimulation on coronary blood flow velocity1998 · 27 citations
  2. 2Effects of spinal cord stimulation on myocardial ischaemia during daily life in patients with severe coronary artery disease. A prospective ambulatory electrocardiographic study.1994 · 157 citations
  3. 3Effect of spinal cord stimulation on myocardial perfusion reserve in patients with refractory angina pectoris2014 · 33 citations
  4. 4Spinal cord stimulation significantly decreases the need for acute hospital admission for chest pain in patients with refractory angina pectoris1999 · 103 citations
  5. 5Management of angina pectoris: the role of spinal cord stimulation.2009 · 16 citations