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January 1, 1998Coronary Artery Disease

Effects of spinal cord stimulation on coronary blood flow velocity

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Why the study?

Does spinal cord stimulation increase coronary flow velocity during cardiac stress in patients with severe angina?

Population

12 patients

Comparison

Spinal cord stimulation commenced during maximum… vs Coronary flow velocity during maximum pacing…

Design

Case_series

Authors

HNHenrik NorrsellSahlgrenska University HospitalTETore EliassonAngered HospitalPAPer AlbertssonInterventional Cardiology

Discussion

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Implication

Spinal cord stimulation may not increase coronary flow velocity during stress; leaves open alternative anti-ischemic mechanisms for study.

Structured PICO

Does spinal cord stimulation increase coronary flow velocity during cardiac stress in patients with severe angina?

P
Population
12 patients (8 with severe anginal pain secondary to coronary artery disease who had been implanted with a spinal cord stimulation device, and 4 with syndrome X)
I
Intervention
Spinal cord stimulation (SCS) commenced during maximum atrial pacing-induced cardiac stress
C
Comparator
Coronary flow velocity during maximum pacing frequency prior to the introduction of spinal cord stimulation (intra-patient comparison)
O
Outcome
Coronary flow velocity, assessed as average peak velocity (APV) using a Doppler guidewiresurrogate

Spinal cord stimulation does not appear to exert its anti-ischemic effects by increasing coronary blood flow velocity during cardiac stress.

Cite This Study

Norrsell et al. (1998) studied this question.

synapsesocial.com/papers/6a95b7a4eea6d966b92bee7bhttps://doi.org/10.1097/00019501-199809050-00005
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of spinal cord stimulation on myocardial perfusion reserve in patients with refractory angina pectoris2014 · 33 citations
  2. 2Effects of spinal cord stimulation in angina pectoris induced by pacing and possible mechanisms of action.1993 · 222 citations
  3. 3Assessment of the influence of spinal cord stimulation on left ventricular function in patients with severe angina pectoris: an echocardiographic study1993 · 49 citations
  4. 4Effects of spinal cord stimulation on myocardial ischaemia during daily life in patients with severe coronary artery disease. A prospective ambulatory electrocardiographic study.1994 · 157 citations
  5. 5Management of angina pectoris: the role of spinal cord stimulation.2009 · 16 citations