Key result
Constipation-predominant IBS with severe pain was associated with lower HF power (P=0.01) and higher LF/HF ratio (P=0.003) compared to diarrhoea-predominant IBS and healthy controls.
Why the study?
Is heart rate variability associated with pain severity and predominant bowel pattern in women with irritable bowel syndrome?
Population
215 women, including those with irritable bowel syndrome and healthy controls recruited from the community.
Design
Cross-sectional
Authors
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Autonomic imbalance suggested in severe-pain constipation-predominant IBS; hypothesis-generating for HRV phenotyping and requires prospective validation.
Observational (n=215)
Is heart rate variability associated with pain severity and predominant bowel pattern in women with irritable bowel syndrome?
p-value: p=0.01 and 0.003
Heart rate variability differs significantly based on predominant bowel pattern in women with irritable bowel syndrome who experience severe gut pain.
Cain et al. (2007) conducted an observational in Irritable bowel syndrome (n=215). Constipation-predominant irritable bowel syndrome with severe gut pain vs. Diarrhoea-predominant irritable bowel syndrome and healthy controls was evaluated on Heart rate variability (high-frequency power and LF/HF ratio) (p=0.01 and 0.003). Constipation-predominant IBS with severe pain was associated with lower HF power (P=0.01) and higher LF/HF ratio (P=0.003) compared to diarrhoea-predominant IBS and healthy controls.
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