Key result
Irritable bowel syndrome was associated with altered heart rate variability compared to healthy controls (P<0.01), with 19% of patients showing an aberrant global profile linked to severe symptoms.
Why the study?
Does heart rate variability differ between patients with irritable bowel syndrome and healthy controls, and is it associated with symptoms?
Population
197 participants, comprising 158 patients with irritable bowel syndrome and 39 healthy controls.
Comparison
Irritable bowel syndrome (IBS) vs Healthy controls (HC)
Design
Case-control
Follow-up
24 hours
Authors
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HRV differences may mark severe-symptom IBS subset; hypothesis-generating, requires prospective validation before clinical use.
Cross-Sectional (n=197)
Does heart rate variability differ between patients with irritable bowel syndrome and healthy controls, and is it associated with symptoms?
p-value: p=<.01
Altered autonomic nervous system function, measured by HRV, is present in a subset of IBS patients and is associated with more severe bowel symptoms.
Polster et al. (2018) conducted a cross-sectional in Irritable bowel syndrome (IBS) (n=197). Irritable bowel syndrome vs. Healthy controls was evaluated on Heart rate variability (HRV) parameters (p=<.01). Irritable bowel syndrome was associated with altered heart rate variability compared to healthy controls (P<0.01), with 19% of patients showing an aberrant global profile linked to severe symptoms.
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