Key result
Management of cardiogenic shock in a patient with Takotsubo and hypertrophic obstructive cardiomyopathy requires avoiding standard inotropes and using fluids, beta-blockers, alpha agonists, or IABP.
Case Report (n=1)
In patients with Takotsubo cardiomyopathy and preexisting HOCM, hypotension should be evaluated for LVOTO and managed with fluids, beta-blockers, alpha agonists, or IABP rather than standard inotropes which can worsen the condition.
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Caution against inotropes in Takotsubo-HOCM shock; single case leaves open need for prospective validation.
•Echocardiography is used to diagnose hypertrophic obstructive cardiomyopathy (HOCM) and Takotsubo cardiomyopathy (TCM).•Hypotension in a patient with TCM should be evaluated for left ventricular outflow tract obstruction (LVOTO).•Management of TCM is challenging in patients with HOCM with severe LVOTO.•Hypotension in LVOTO may paradoxically worsen with standard intravenous inotropes.•Fluid resuscitation, beta-blockers, alpha agonists, and intra-aortic balloon pump are the treatment options in LVOTO.
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Nalluri et al. (2017) conducted a case report in Cardiogenic Shock Secondary to Takotsubo Cardiomyopathy and Hypertrophic Obstructive Cardiomyopathy (n=1). Fluid resuscitation, beta-blockers, alpha agonists, and intra-aortic balloon pump was evaluated. Management of cardiogenic shock in a patient with Takotsubo and hypertrophic obstructive cardiomyopathy requires avoiding standard inotropes and using fluids, beta-blockers, alpha agonists, or IABP.
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