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July 1, 2001Journal of Biological ChemistryOpen Access

Calpain Cleavage Promotes Talin Binding to the β3Integrin Cytoplasmic Domain

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BYBoxu YanScripps Research InstituteDCDavid CalderwoodYale Cancer CenterBYBrian L. YaspanHeidelberg University

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Cite This Study

Yan et al. (2001) studied this question.

synapsesocial.com/papers/6a95bb33a72d156b91d033d9https://doi.org/10.1074/jbc.m104161200
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Probing Chemical and Conformational Differences in the Resting and Active Conformers of Platelet Integrin αIIbβ32000 · 55 citations
  2. 2Mutational Evidence for Control of Cell Adhesion Through Integrin Diffusion/Clustering, Independent of Ligand Binding1997 · 174 citations
  3. 3Muscle β1D Integrin Reinforces the Cytoskeleton–Matrix Link: Modulation of Integrin Adhesive Function by Alternative Splicing1997 · 128 citations
  4. 4The Platelet Cytoskeleton Regulates the Affinity of the Integrin αIIbβ3 for Fibrinogen1999 · 83 citations
  5. 5Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site1996 · 266 citations