November 30, 1956American Journal of Physiology-Legacy Content

Effect of Volume and Rate of Inflation and Deflation on Transpulmonary Pressure and Response of Pulmonary Stretch Receptors

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Population

anesthetized cats with open thoraxes

Design

Preclinical

Authors

HDHarry L. DavisMayo Clinic WFWard S. FowlerCentre College ELEdward H. LambertAtlantic International University

Discussion

Member takes

Implication

Animal data on pulmonary stretch receptor dynamics warrant no practice change; leaves open human mechanistic validation.

Structured PICO

Population

anesthetized cats with open thoraxes

Intervention

varied volumes and rates of inflation and deflation of the lungs

Outcome

Action potentials of single vagal afferent nerve fibers from slowly adapting pulmonary stretch receptors, transpulmonary pressure and rate of air flowsurrogate

Slowly adapting pulmonary stretch receptors provide signals related to the work of breathing, with discharge frequency varying by lung volume and rate of change.

Cite This Study

Davis et al. (1956) studied this question.

synapsesocial.com/papers/6a95bf171b727dc4cbbaeb1a https://doi.org/10.1152/ajplegacy.1956.187.3.558

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Effect of Volume and Rate of Inflation and Deflation on Transpulmonary Pressure and Response of Pulmonary Stretch Receptors

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Effect of Volume and Rate of Inflation and Deflation on Transpulmonary Pressure and Response of Pulmonary Stretch Receptors

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider