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Case report reveals Hemophilus aphrophilus empyema and pneumonia in an adult, highlighting an expanded spectrum of invasive bacterial disease.
Case Studies1 April 1965Hemophilus Aphrophilus EmpyemaJOHN P. CAPELLI, M.D., J. WOODROW SAVACOOL, M.D., EILEEN L. RANDALL, PH.D.JOHN P. CAPELLI, M.D.Search for more papers by this author, J. WOODROW SAVACOOL, M.D.Search for more papers by this author, EILEEN L. RANDALL, PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-4-771 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA little-known bacillus that has recently stimulated the interest of bacteriologists and that has appeared in certain important clinical situations isHemophilus aphrophilus. The organism was first described in 1940 by Khairat (1) in association with a fatal case of endocarditis. It was not reported in association with clinical disease again until 1958. At that time, Toschach and Bain (2) described a second case of endocarditis. A total of seven cases ofH. aphrophilusendocarditis and one case of a brain abscess have been described (3-5), but pneumonia and empyema due to this organism have not been reported. The present...References1. KHAIRAT O: Endocarditis due to a new species of Haemophilus. J. Path. Bact. 33· 497, 1940. CrossrefGoogle Scholar2. TOSCHACHBAIN SGO: Acquired aortic sinus aneurysm caused by Hemophilus aphrophilus. J. Clin. Path. 30: 328, 1958. CrossrefGoogle Scholar3. VARGASGILALERTKOHAN LPBR: Endocarditis bacteriana por Hemophilus aphrophilus. Rev. Chile Pediat. 33: 183, 1962. MedlineGoogle Scholar4. WITORSCHGORDEN PP: Hemophilus aphrophilus endocarditis. Ann. Intern. Med. 60: 957, 1964. LinkGoogle Scholar5. FAGER CA: An unusual brain abscess: report of a case. Lahey Clin. Bull. 12: 108, 1961. MedlineGoogle Scholar6. KINGTATUM EOHW: Actinobacillus actinomycetemcomitans and Hemophilus aphrophilus. J. Infect. Dis. 111: 85, 1962. CrossrefMedlineGoogle Scholar7. BREEDMURRAYSMITH RSEGNR: Bergey's Manual of Determinative Bacteriology, 7th ed., The Williams and Wilkins Co., Baltimore, 1957, p. 395. Google Scholar8. WILSONMILES GSAA: Topley and Wilson's Principles of Bacteriology and Immunology, 4th ed., The Williams and Wilkins Co., Baltimore, 1955, p. 890. Google Scholar9. THJØTTAHENRIKSON TSD: Pneumonia and empyema caused by a pasteurella of the hemorrhagic septicemia group. Acta Path. Microbiol. Scand. 23: 412, 1946. CrossrefGoogle Scholar10. ATINBEETHAM HLWP: Pasteurella multocida empyema. New Eng. J. Med. 256: 979, 1957. CrossrefMedlineGoogle Scholar11. DEBOERDUMBER RGM: Pasteurella multocida infections. Amer. J. Clin. Path. 40: 339, 1963. CrossrefMedlineGoogle Scholar12. SCHIPPER GJ: Unusual pathogenicity of pasteurella multocida isolated from the throats of common wild rats. Bull. Hopkins Hosp. 81: 333, 1947. MedlineGoogle Scholar13. KEITHLYON TASA: Hemophilus aphrophilus endocarditis. Amer. J. Med. 34: 535, 1963. CrossrefMedlineGoogle Scholar14. ORYJACKSONFINLAND EMGGM: Gram-negative bacillus empyema cured by intrapleural penicillin. JAMA 131: 1035, 1946. CrossrefMedlineGoogle Scholar15. OLSENNEEDHAM AMGM: Pasteurella multocida in suppurative diseases of the respiratory tract. Amer. J. Med. Sci. 224: 77, 1952. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JOHN P. CAPELLI, M.D.; J. WOODROW SAVACOOL, M.D.; EILEEN L. RANDALL, PH.D.Affiliations: Philadelphia, PennsylvaniaFrom the Department of Medicine and Clinical Laboratories of the Jefferson Medical College and Hospital, Philadelphia, Pa.Requests for reprints should be addressed to J. Woodrow Savacool, M.D., 255 S. 17th Street, Philadelphia, Pa. 19103. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEmpyema due to Aggregatibacter aphrophilus and Parvimonas micra CoinfectionEmpiema secundario a coinfección por Aggregatibacter aphrophilus y Parvimonas micraAggregatibacter aphrophilus in a patient with recurrent empyema: a case reportSevere Pulmonary Infection by Haemophilus Aphrophilus in a Non-compromised ChildEikenella Corrodens and Other Similar Bacteria: A Review of Laboratory Aspects and Clinical SignificanceAortic Insufficiency due to Hemophilus Aphrophilus with Prosthetic Valve ReplacementHAEMOPHILUS APHROPHILUS INFECTIONS: CLINICAL AND BACTERIOLOGIC STUDIESSubacute bacterial endocarditis caused by a micro-organism resemblingHaemophilus aphrophilus 1 April 1965Volume 62, Issue 4Page: 771-777KeywordsAbscessesBacillusBrainClinical laboratoriesEndocarditisHaemophilusHospital medicinePathogensPenicillinPneumonia ePublished: 1 December 2008 Issue Published: 1 April 1965 PDF downloadLoading ...
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