Why the study?
Does propofol reduce the hypertensive response compared to methohexital in patients undergoing electroconvulsive therapy?
Population
15 patients undergoing courses of six electroconvulsive therapy (ECT) administrations
Comparison
Propofol (induction dose 1.60 +/- 0.04 mg/kg) vs Methohexital (induction dose 1.08 +/- 0.03 mg/kg)
Design
Other
Follow-up
During courses of six ECT administrations
Authors
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Propofol may attenuate hypertensive response in ECT; leaves open optimal agent choice and seizure adequacy pending randomized trials.
Does propofol reduce the hypertensive response compared to methohexital in patients undergoing electroconvulsive therapy?
Propofol effectively attenuates the transient hypertensive response associated with electroconvulsive therapy compared to methohexital, though it also reduces seizure duration.
RAMPTON et al. (1989) studied this question.
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