Key result
Intermittent pneumatic compression did not significantly improve disability (adjusted OR 0.98; 95% CI 0.80-1.19; p=0.83), living circumstances, or quality of life at 6 months post-stroke.
Why the study?
Does intermittent pneumatic compression improve disability, living circumstances, quality of life, and hospital costs in immobile patients with stroke?
Population
2876 immobile patients with stroke from days 0 to 3 of admission
Comparison
Intermittent pneumatic compression (IPC) vs No IPC
Design
RCT, 1:1 ratio with a computer-generated allocation sequence through a central…
Follow-up
about 6 months
Authors
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Does not support use for functional recovery in immobile stroke patients; confirms benefits confined to DVT prevention and survival.
RCT (n=2,876)
Partially masked
1:1
Yes
Does intermittent pneumatic compression improve disability, living circumstances, quality of life, and hospital costs in immobile patients with stroke?
Odds Ratio: 0.98 (95% CI 0.8–1.19)
p-value: p=0.83
In immobile stroke patients, intermittent pneumatic compression prevents DVT and improves survival but does not improve functional outcomes or quality of life at 6 months.
Martin Dennis (2014) conducted an RCT in immobile patients with stroke (n=2,876). Intermittent pneumatic compression vs. No intermittent pneumatic compression was evaluated on disability (Oxford Handicap Scale 0-2 vs 3-6) (adjusted OR 0.98, 95% CI 0.80 to 1.19, p=0.83). Intermittent pneumatic compression did not significantly improve disability (adjusted OR 0.98; 95% CI 0.80-1.19; p=0.83), living circumstances, or quality of life at 6 months post-stroke.
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