Key result
Intermittent pneumatic compression significantly reduced the incidence of deep vein thrombosis in stroke patients (RR 0.50; 95% CI 0.27-0.94) but increased IPC-related adverse events.
Why the study?
Does intermittent pneumatic compression reduce the risk of DVT, PE, and mortality in stroke patients?
Population
3,551 stroke patients from 7 randomized controlled trials
Comparison
Intermittent pneumatic compression (IPC) vs No IPC
Design
Meta-analysis
Follow-up
6 months
Authors
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Supports selective IPC for DVT prophylaxis in stroke; reinforces meta-analytic evidence while cautioning on adverse event trade-offs.
Meta-Analysis (n=3,551)
Does intermittent pneumatic compression reduce the risk of DVT, PE, and mortality in stroke patients?
Relative Risk: 0.5 (95% CI 0.27–0.94)
Intermittent pneumatic compression significantly reduces the risk of DVT in stroke patients but increases adverse events and does not meaningfully improve quality-adjusted survival.
Zhang et al. (2018) conducted a meta-analysis in stroke (n=3,551). Intermittent pneumatic compression (IPC) vs. no IPC was evaluated on incidence of deep vein thrombosis (DVT) (RR 0.50, 95% CI 0.27, 0.94). Intermittent pneumatic compression significantly reduced the incidence of deep vein thrombosis in stroke patients (RR 0.50; 95% CI 0.27-0.94) but increased IPC-related adverse events.
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