Why the study?
Does combined parasympathetic and sympathetic blockade affect left ventricular relaxation at rest and during exercise differently in trained versus untrained men?
Population
18 men (8 endurance-trained and 10 untrained subjects)
Comparison
Autonomic blockade with intravenous propranolol… vs Pre-blockade conditions (baseline)
Design
Other
Authors
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Supports autonomic mediation of athletes' diastolic advantages; hypothesis-generating and should not yet alter practice.
Does combined parasympathetic and sympathetic blockade affect left ventricular relaxation at rest and during exercise differently in trained versus untrained men?
Enhanced diastolic relaxation observed in endurance athletes appears to be mediated by training-induced adaptations of the autonomic nervous system.
Nieß et al. (1996) studied this question.
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