Key result
This historical review outlines the development and technological advancement of the buffy coat method for platelet concentrates in the Netherlands since the 1970s.
Why the study?
The need for platelet concentrates sharply increased in the 1970s due to better treatment regimens for oncohaematological diseases, prompting the standardization and automation of blood production processes.
Provides a historical overview of the development and standardization of the buffy coat method for platelet concentrates in the Netherlands.
Answers are grounded in this paper and cite their sources.
Enduring buffy coat use in platelet production warrants ongoing standardization review; extends historical context for transfusion process optimization.
The buffy coat method as a source for platelet concentrates was developed in the 1970s and is still used in many blood centres around the world. Development of the method sparked various technological advances in blood collection, processing and storage. At the time, the need for platelet concentrates sharply increased because of better treatment regimens for (onco)haematological diseases, which forced blood centres to standardize and automate their production processes as much as the technology would allow. In this review, a historical overview of the Dutch experiences is provided in the context of the international developments.
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Meer et al. (2022) reported a review. Buffy coat method for platelet concentrates was evaluated. This historical review outlines the development and technological advancement of the buffy coat method for platelet concentrates in the Netherlands since the 1970s.
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