Key result
Metabolic profiling of cardiac tissue using high-resolution NMR spectroscopy and multivariate statistics successfully separated mouse models of cardiac disease from their control strains.
Metabolic profiling using NMR spectroscopy and multivariate statistics is a rapid and effective method for phenotyping mouse models of cardiac disease.
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May enable rapid phenotyping of mouse cardiac models; leaves open human translation.
Jones et al. (2004) studied Cardiac disease. Metabolic profiling through high resolution NMR spectroscopy vs. Control strain was evaluated on Separation of each mouse model from its control strain. Metabolic profiling of cardiac tissue using high-resolution NMR spectroscopy and multivariate statistics successfully separated mouse models of cardiac disease from their control strains.
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