Key result
Atherosclerosis is characterized by vascular inflammation and endothelial dysfunction, which can be diagnosed via biomarkers and imaging, and managed with ACE inhibitors, statins, and antioxidants.
This review summarizes the pathophysiology of atherosclerosis, emphasizing the role of inflammation, endothelial dysfunction, and the therapeutic potential of ACE inhibitors, ARBs, statins, and antioxidants.
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Supports statin/ACE inhibitor use in atherosclerosis; leaves open prospective validation of antioxidant and biomarker strategies.
Tousoulis et al. (2011) conducted a review in Atherosclerosis. Atherosclerosis is characterized by vascular inflammation and endothelial dysfunction, which can be diagnosed via biomarkers and imaging, and managed with ACE inhibitors, statins, and antioxidants.
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