Key result
TaqMan CMV quantitative PCR showed a strong linear correlation with the CMV antigenemia test for monitoring CMV infection in transplant recipients (R=0.843, P=0.001).
Why the study?
Does real-time TaqMan CMV quantitative PCR correlate with the CMV antigenemia test for monitoring CMV infection in heart and lung transplant patients?
Population
25 heart transplant and single-lung transplant patients monitored posttransplantation
Comparison
Real-time TaqMan CMV quantitative PCR from EDTA… vs CMV antigenemia test
Design
Cohort
Authors
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Supports TaqMan CMV qPCR as potential alternative for post-transplant monitoring; leaves open prospective validation before practice change.
Observational (n=25)
Does real-time TaqMan CMV quantitative PCR correlate with the CMV antigenemia test for monitoring CMV infection in heart and lung transplant patients?
Effect estimate: R=0.843
p-value: p=0.001
TaqMan CMV QPCR is an accurate and robust alternative to the antigenemia test for monitoring CMV infection in heart and lung transplant recipients.
Guiver et al. (2001) conducted an observational in CMV infection (n=25). TaqMan CMV quantitative PCR vs. CMV antigenemia test was evaluated on Correlation between antigenaemia levels and TaqMan CMV QPCR genome copies (R=0.843, p=0.001). TaqMan CMV quantitative PCR showed a strong linear correlation with the CMV antigenemia test for monitoring CMV infection in transplant recipients (R=0.843, P=0.001).
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