Key result
Higher pre-operative systolic blood pressure variability, measured by standard deviation, significantly increased the risk of major adverse cardiac events within one year after percutaneous coronary intervention (OR 1.049).
Why the study?
Whether pre-operative blood pressure variability adversely affects outcomes after percutaneous coronary intervention was unclear.
Does elevated pre-operative day-to-day blood pressure variability predict poor outcomes in patients undergoing PCI?
Cohort (n=471)
No
Does elevated pre-operative day-to-day blood pressure variability predict poor outcomes in patients undergoing PCI?
Odds Ratio: 1.049 (95% CI 1.003–1.1)
Pre-operative day-to-day blood pressure variability predicts adverse outcomes up to one year following PCI, serving as a potential marker for risk stratification.
May support preoperative BP variability assessment for PCI risk stratification; leaves open causality and need for prospective trials.
BACKGROUND: For patients with cardiovascular disease, blood pressure variability (BPV), distinct from hypertension, is an important determinant of adverse cardiac events. Whether pre-operative BPV adversely affects outcomes after percutaneous coronary intervention (PCI) is to this point unclear. AIM: To investigate the relationship between blood pressure variability and outcomes for patients post-PCI. METHODS: = 471). Adverse outcomes were identified up to a year following the procedure, including major adverse cardiac events (MACE), myocardial infarction, cerebrovascular accident, death, and all-cause hospitalization. RESULTS: < 0.05). CONCLUSION: As BPV is easily measured and captured in the electronic medical record, these findings describe a novel method of identifying at-risk patients who undergo PCI. Aggressive risk modification for patients with elevated BPV and known coronary artery disease is indicated.
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Weisel et al. (2022) conducted a cohort in Coronary artery disease requiring percutaneous coronary intervention (n=471). Pre-operative blood pressure variability vs. Lower blood pressure variability was evaluated on Major adverse cardiac events (MACE) within 1 year (OR 1.049, 95% CI 1.003-1.100). Higher pre-operative systolic blood pressure variability, measured by standard deviation, significantly increased the risk of major adverse cardiac events within one year after percutaneous coronary intervention (OR 1.049).
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