Key result
LVEF fails to improve long-term in eosinophilic myocarditis, while baseline NT-proBNP and LVEF predict remodeling.
Why the study?
Due to the rarity and heterogeneity of eosinophilic myocarditis, diagnosis and risk-adapted treatment remain challenging, and longitudinal data on cardiac function are scarce.
Population
51 patients with eosinophilic myocarditis treated at Ludwig-Maximilians-University Hospital in Munich
Design
Retrospective cohort study
Follow-up
Median of 34 months [interquartile range 16–79]
Authors
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May inform prognosis in eosinophilic myocarditis; extends Sartorelli score but remains hypothesis-generating pending prospective validation.
Cohort (n=51)
No
Effect estimate: Δ + 3 ± 12%
p-value: p=0.57
In patients with eosinophilic myocarditis, baseline NT-proBNP, LVEF, and the Sartorelli score are strong predictors of long-term cardiac function and remodeling, highlighting their potential utility for risk stratification.
Ullrich et al. (2026) conducted a cohort in Eosinophilic myocarditis (n=51). Eosinophilic myocarditis was evaluated on Change in left-ventricular ejection fraction (LVEF) from baseline to final follow-up (Δ + 3 ± 12%, p=0.57). In patients with eosinophilic myocarditis, mean left-ventricular ejection fraction did not significantly improve over a median of 34 months (Δ + 3 ± 12%, p = 0.57), and baseline NT-proBNP, LVEF, and Sartorelli score predicted long-term cardiac remodeling.