Key result
Children with congenital heart disease reported a 2.3-point higher health-related quality of life score compared to healthy peers after adjusting for age and sex (P<0.001).
Why the study?
Does congenital heart disease reduce health-related quality of life in children and adolescents compared to healthy peers?
Population
514 children and adolescents with congenital heart disease, aged 7-17 years, including 191 girls.
Comparison
Presence of congenital heart disease vs 734 healthy children
Design
Cross-sectional
Authors
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Suggests preserved HRQoL in pediatric CHD; leaves open resilience factors and requires prospective confirmation.
Cross-Sectional (n=1,248)
No
Does congenital heart disease reduce health-related quality of life in children and adolescents compared to healthy peers?
Mean Difference: 2.3
Absolute Event Rate: 78.6% vs 75.6%
p-value: p=<0.001
Children and adolescents with congenital heart disease report health-related quality of life that is equal to or better than their healthy peers, regardless of disease severity.
Reiner et al. (2018) conducted a cross-sectional in Congenital heart disease (n=1,248). Congenital heart disease vs. Healthy peers was evaluated on Health-related quality of life (HRQoL) assessed by KINDL questionnaire (MD 2.3, p=<0.001). Children with congenital heart disease reported a 2.3-point higher health-related quality of life score compared to healthy peers after adjusting for age and sex (P<0.001).
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