Key result
A mathematical model of oxidative phosphorylation successfully reproduced experimental flux-force relationships, time courses, P/O ratios, and threshold curves under various conditions.
Population
Mathematical model of oxidative phosphorylation (OXPHOS)
Design
Other
Authors
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New OXPHOS model reproduces key experimental behaviors; leaves open validation for cardiac bioenergetics research.
A newly developed mathematical model of oxidative phosphorylation accurately reproduces experimental mitochondrial function, providing a tool to study physiological and pathological energy metabolism.
Heiske et al. (2017) studied Mitochondrial function / Oxidative phosphorylation. Mathematical model of oxidative phosphorylation was evaluated on Flux-force relationships, time courses, P/O ratios, and threshold curves. A mathematical model of oxidative phosphorylation successfully reproduced experimental flux-force relationships, time courses, P/O ratios, and threshold curves under various conditions.
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