Key result
24 hours of caffeine abstinence resulted in a higher heart rate response 5 minutes after adenosine infusion compared to 12 hours (79.4 vs 76.8, p=0.009).
Why the study?
Does 24 hours of caffeine abstinence compared to 12 hours improve heart rate response to adenosine in patients undergoing adenosine stress myocardial perfusion imaging?
Population
729 patients with suspected ischemic heart disease undergoing adenosine stress thallium-201 myocardial…
Comparison
24 hours of caffeine abstinence prior to… vs 12 hours of caffeine abstinence prior to…
Design
Cohort
Follow-up
6 minutes post-infusion
Authors
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No significant HR difference after 12 vs 24 h caffeine abstinence; leaves open whether shorter abstinence suffices for adenosine MPI.
Observational (n=729)
Does 24 hours of caffeine abstinence compared to 12 hours improve heart rate response to adenosine in patients undergoing adenosine stress myocardial perfusion imaging?
Absolute Event Rate: 79.4% vs 76.8%
p-value: p=0.009
A 24-hour caffeine abstinence period yields a better heart rate response to adenosine during myocardial perfusion imaging compared to a 12-hour abstinence period.
Kashima et al. (2016) conducted an observational in suspected ischemic heart disease (n=729). 24 hours of caffeine abstinence vs. 12 hours of caffeine abstinence was evaluated on Heart rate at 5 minutes after adenosine infusion (p=0.009). 24 hours of caffeine abstinence resulted in a higher heart rate response 5 minutes after adenosine infusion compared to 12 hours (79.4 vs 76.8, p=0.009).
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