Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 22, 2022Гематология и трансфузиологияOpen Access

vWF is an important predictor of stroke development in patients with AF based on a meta-analysis of 12 studies and 7,449 patients.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Von Willebrand factor plasma concentration is not included in modern stroke risk stratification scales in patients with AF.

Does estimation of plasma von Willebrand factor concentration predict stroke development in patients with atrial fibrillation?

Population

7449 patients with AF across 12 studies

Comparison

vWF plasma concentration levels

Design

Meta-analysis of 12 studies

Authors

АРА. О. РубаненкоОРО. А. Рубаненко

Discussion

Loading...

Member takes

Overview

May refine anticoagulation decisions in low-risk AF; extends CHA2DS2-VASc data but requires prospective validation.

Structured PICO

Does estimation of plasma von Willebrand factor concentration predict stroke development in patients with atrial fibrillation?

P
Population
7,449 patients with atrial fibrillation (pooled from 12 studies)
I
Intervention
Estimation of plasma von Willebrand factor (vWF) concentration
O
Outcome
Stroke developmenthard clinical

Determining vWF concentration may be useful for deciding on anticoagulant therapy in AF patients with low risk or a single non-sex CHA2DS2-VASc risk factor.

Cite This Study

Рубаненко et al. (2022) studied this question.

synapsesocial.com/papers/6a968cbc7c15eaca02578172https://doi.org/10.35754/0234-5730-2022-67-3-419-425
View Full Paper
Ask AI
Bookmark
Share