Why the study?
Does oral poliovirus vaccine (OPV) provide superior mucosal immunity compared to inactivated poliovirus vaccine (IPV) in children?
Does oral poliovirus vaccine (OPV) provide superior mucosal immunity compared to inactivated poliovirus vaccine (IPV) in children?
OPV provides superior gastrointestinal mucosal immunity compared to IPV, which is important for inhibiting person-to-person transmission of poliovirus.
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OPV may aid transmission control via superior gut immunity; leaves open optimal IPV-OPV strategies in eradication programs.
John F. Modlin (1991) studied this question.
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