Key result
Catecholamines stimulated myocardial triglyceride lipolysis and fatty acid oxidation in a concentration-dependent manner in isolated rat hearts, an effect inhibited by the presence of palmitate.
The presence of exogenous free fatty acids minimizes the mobilization of endogenous triglycerides in response to catecholamine stimulation in the isolated rat heart.
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Exogenous FFAs blunt catecholamine-driven lipolysis in rat hearts; leaves open translation to human stress metabolism.
Mf et al. (1975) studied this question. Epinephrine and norepinephrine vs. absence of catecholamines was evaluated on triglyceride and glycogen metabolism and contractility. Catecholamines stimulated myocardial triglyceride lipolysis and fatty acid oxidation in a concentration-dependent manner in isolated rat hearts, an effect inhibited by the presence of palmitate.
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