Why the study?
Few studies are available regarding the relationship between diabetes duration and major adverse cardiac events after PCI.
Does longer diabetes duration increase the risk of major adverse cardiac events in diabetic patients undergoing elective PCI?
Population
302 diabetic patients undergoing elective PCI with DES or PTCA using a DCB
Comparison
Diabetes duration <5 years vs 5-10 years vs ≥10 years
Design
Prospective cohort study
Follow-up
12 months
Key result
Longer diabetes duration (≥10 years) was independently associated with an increased risk of myocardial infarction (HR 5.525; 95% CI 1.273-23.978; P=0.022) and repeat revascularization after PCI.
Authors
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May warrant closer post-PCI surveillance in long-duration diabetes; leaves open prospective validation of duration as a risk modifier.
Cohort (n=302)
Does longer diabetes duration increase the risk of major adverse cardiac events in diabetic patients undergoing elective PCI?
Hazard Ratio: 5.525 (95% CI 1.273–23.978)
p-value: p=0.022
In diabetic patients undergoing elective PCI, a diabetes duration of ≥10 years is associated with significantly higher rates of myocardial infarction and repeat revascularization at 12 months compared to shorter disease duration.
Benjamin et al. (2021) conducted a cohort in Type-2 Diabetes and Coronary Artery Disease (n=302). Longer diabetes duration (≥10 years) vs. Shorter diabetes duration (<10 years) was evaluated on Myocardial infarction (HR 5.525, 95% CI 1.273-23.978, p=0.022). Longer diabetes duration (≥10 years) was independently associated with an increased risk of myocardial infarction (HR 5.525; 95% CI 1.273-23.978; P=0.022) and repeat revascularization after PCI.