Why the study?
Diabetes mellitus increases mortality in AMI, but the impact of diabetes duration on long-term outcomes following PCI after a first AMI remains unclear.
Does a diabetes duration of ≥5 years increase the risk of MACCEs in type 2 diabetic patients undergoing primary PCI after their first myocardial infarction compared to a duration of <5 years?
Population
394 type 2 DM patients with PCI after first AMI
Comparison
Diabetes duration ≥5 years vs <5 years
Key result
Diabetes duration ≥5 years was independently associated with an increased risk of MACCEs after PCI for a first myocardial infarction (HR 1.963; 95% CI 1.376-2.801; p<0.001).
Authors
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May aid post-MI PCI risk stratification in diabetes; leaves open prospective validation and targeted interventions.
Cohort (n=394)
Does a diabetes duration of ≥5 years increase the risk of MACCEs in type 2 diabetic patients undergoing primary PCI after their first myocardial infarction compared to a duration of <5 years?
Hazard Ratio: 1.963 (95% CI 1.376–2.801)
p-value: p=< 0.001
A diabetes duration of ≥5 years is an independent predictor of worse long-term clinical outcomes in patients with type 2 diabetes undergoing primary PCI for their first myocardial infarction.
Yaliqin et al. (2024) conducted a cohort in Type 2 diabetes mellitus with acute myocardial infarction (n=394). Long diabetes duration (≥5 years) vs. Short diabetes duration (<5 years) was evaluated on Major adverse cardiovascular and cerebrovascular events (MACCEs) (HR 1.963, 95% CI 1.376-2.801, p=< 0.001). Diabetes duration ≥5 years was independently associated with an increased risk of MACCEs after PCI for a first myocardial infarction (HR 1.963; 95% CI 1.376-2.801; p<0.001).
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