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This theoretical review summarizes current research on the psychophysiological and molecular-genetic correlates of fatigue, highlighting the roles of EEG rhythms and serotonin/dopamine polymorphisms.
This review highlights the shift towards an integral approach in studying fatigue, incorporating recent advances in molecular biology to understand psychophysiological and molecular-genetic correlates.
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Should not change clinical fatigue assessment; leaves open targeted validation of EEG and genetic correlates.
The article is devoted to a theoretical overview in the field of fatigue, and in particular to recent data on psychophysiological and molecular-genetic correlates of fatigue. Nowadays there exist many methods used to assess fatigue and other functional states: subjective, behavioral and physiological methods. Earlier the studies in the area of fatigue were mainly focused on looking for an objective indicator. The current research focuses on an integral approach. Over recent years the significant progress in molecular biology has been achieved, which provided a significant impact on quality and scope of investigations. Now we can find numerous researches which reflect the link between the presence of certain polymorphisms and expression of behavioral patterns or physiological reactions. Thus, in the present study we make an attempt to reflect the existing psycho-physiological and molecular-genetic correlates of fatigue.
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Поликанова et al. (2016) conducted a review in Fatigue. This theoretical review summarizes current research on the psychophysiological and molecular-genetic correlates of fatigue, highlighting the roles of EEG rhythms and serotonin/dopamine polymorphisms.
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