Key result
R0 resection in the first surgery for retroperitoneal liposarcoma significantly improved 5-year recurrence-free survival compared to non-R0 resection (49% vs 29%, P=0.033).
Why the study?
The characteristics of primary and repeated recurrent retroperitoneal liposarcoma needed to be investigated.
Does R0 resection improve recurrence-free survival in patients with primary retroperitoneal liposarcoma compared to non-R0 resection?
Comparison
R0 resection vs non-R0 resection in the first surgery
Design
Retrospective study
Authors
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Supports R0 resection attempt in initial surgery; extends observational data but leaves open need for prospective validation.
Cohort (n=52)
No
Does R0 resection improve recurrence-free survival in patients with primary retroperitoneal liposarcoma compared to non-R0 resection?
Absolute Event Rate: 49% vs 29%
p-value: p=0.033
R0 resection during the initial surgery for primary retroperitoneal liposarcoma is associated with significantly improved recurrence-free survival, whereas repeated surgeries for recurrences yield progressively shorter recurrence-free intervals.
Ishii et al. (2020) conducted a cohort in Retroperitoneal liposarcoma (n=52). R0 resection vs. non-R0 resection was evaluated on 5-year recurrence-free survival (p=0.033). R0 resection in the first surgery for retroperitoneal liposarcoma significantly improved 5-year recurrence-free survival compared to non-R0 resection (49% vs 29%, P=0.033).
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