Why the study?
Does elevated sympathetic activity occur in spontaneously hypertensive rats compared to normotensive rats?
Does elevated sympathetic activity occur in spontaneously hypertensive rats compared to normotensive rats?
The study provides physiological evidence of elevated sympathetic activity in both the development and maintenance phases of spontaneous hypertension in a rat model.
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Supports sympathetic hyperactivity in SHR hypertension phases; leaves open translation to human disease and therapy.
Schramm et al. (1979) studied this question.
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