Key result
Contrast-enhanced CT numbers were significantly lower in unstable carotid plaques (35.4 HU) compared to stable plaques (80.2 HU) defined by BB-MRI, showing a significant negative correlation.
Why the study?
Does contrast-enhanced CT correlate with black blood MRI in evaluating carotid artery plaques in patients with severe carotid artery stenosis?
Observational (n=35)
No
Does contrast-enhanced CT correlate with black blood MRI in evaluating carotid artery plaques in patients with severe carotid artery stenosis?
Absolute Event Rate: 35.4% vs 80.2%
p-value: p=0.0003
Contrast-enhanced CT correlates well with black blood MRI for evaluating carotid artery plaques and can serve as a useful adjunctive diagnostic tool when MRI is contraindicated.
May support contrast-enhanced CT for plaque assessment when MRI unavailable; leaves open prospective outcome validation.
頸部頸動脈狭窄症ステント留置術前評価法として行ったMRI BB法と造影CTによるプラーク診断の相関につき検討した．【方法】CASを施行した35症例を対象とした．【結果】MRI BB法における不安定プラーク群(Unstable群)は19例，安定プラーク群(Stable群)は16例であり，プラーク内CT値の平均値はU群35.4 HU，S群80.2 HUとなり有意差を認めた(p < 0.01)．またHU値とMRI T1 Plaque/Muscle比間には負の相関が見られた(r = －0.589，p < 0.01)．【結論】MRI施行不能例において造影CTはプラーク診断における補助的診断法になり得る．
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Inukai et al. (2010) conducted an observational in Carotid artery stenosis (n=35). Contrast-enhanced computed tomography (CE-CT) vs. Black-blood magnetic resonance imaging (BB-MRI) was evaluated on Average CT number (HU) in unstable versus stable plaque groups defined by BB-MRI (p=0.0003). Contrast-enhanced CT numbers were significantly lower in unstable carotid plaques (35.4 HU) compared to stable plaques (80.2 HU) defined by BB-MRI, showing a significant negative correlation.
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