Key result
Late acute rejection occurred in 19 of 32 long-term cardiac transplant survivors, with incidence decreasing from 1 episode per 20.5 patient days initially to 1 per 200 days after 4 months.
Cohort (n=59)
No
Late acute rejection in long-term cardiac transplant survivors decreases in frequency over time, is often clinically mild, and can usually be managed with increased oral prednisone without precluding good long-term graft function.
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Late rejection frequency falls after 4 months in cardiac allograft recipients; leaves open optimal surveillance duration in long-term survivors.
Graham et al. (1974) conducted a cohort in Cardiac transplantation (n=59). Long-term survival post-cardiac transplantation was evaluated on Late acute rejection episodes. Late acute rejection occurred in 19 of 32 long-term cardiac transplant survivors, with incidence decreasing from 1 episode per 20.5 patient days initially to 1 per 200 days after 4 months.
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