Population
Mammalian hearts (endogenous adult cardiac progenitor cells)
Design
Review
Key result
This review documents the various reported stem and progenitor cell populations in mammalian hearts and discusses the current state of knowledge on their origins and lineage capabilities.
Authors
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Minor baseline cardiomyocyte contribution from cardiac progenitors warrants caution against premature use; leaves open potential for therapeutic augmentation in future studies.
This review summarizes the origins and lineage capabilities of endogenous adult cardiac progenitor cells, highlighting their minor baseline contribution to new cardiomyocytes but potential for therapeutic augmentation.
Chong et al. (2014) conducted a review in Cardiac stem and progenitor cell populations. This review documents the various reported stem and progenitor cell populations in mammalian hearts and discusses the current state of knowledge on their origins and lineage capabilities.
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