Key result
In vitro cellular models of cardiomyocyte de-differentiation provide insights into the pathophysiology of hibernating myocardium and may help identify novel therapeutic strategies.
Population
In vitro model of cardiomyocyte de-differentiation
Design
Editorial
Authors
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May inform preclinical testing for hibernating myocardium; leaves open clinical translation of de-differentiation models.
Cellular models of hibernating myocardium may help elucidate its pathophysiology and facilitate in vitro testing of novel therapies to halt or reverse phenotypic changes.
G. Chad Hughes (2001) conducted an editorial in Hibernating myocardium. In vitro cellular models of cardiomyocyte de-differentiation provide insights into the pathophysiology of hibernating myocardium and may help identify novel therapeutic strategies.
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