Population
Xenopus oocytes heterologously expressing HERG potassium channels
Design
Preclinical
Authors
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May inform preclinical arrhythmia models; leaves open clinical anti-arrhythmic translation.
Bertosamil blocks HERG potassium channels in their open and inactivated states, providing a mechanistic basis for its anti-arrhythmic properties.
Zitron et al. (2002) studied this question.
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